Since I switched to 2.6.4 (win 32 vista), I had several occurrences of

-break-insert
"\"B:/lazarus_latest/components/fpdebug/fppascalbuilder.pas\":387 ^done,bkpt={number="12",type="breakpoint",disp="keep",enabled="y",addr="0x00000055",file="fppascalbuilder.pas",line="387",times="0,original-location="\"B:/lazarus_latest/components/fpdebug/fppascalbuilder.pas\":387"} ^error,msg="Warning:\nCannot insert breakpoint 12.\nError accessing memory address 0x55: Input/output error.\n"

It appears that -Xe fixes the issue.

I have not yet had the time to go back and test under 2.6.2.

Does anyone know, if there where changes that may have caused this?